Hit to Lead also known as lead generation is a prerequisite for the construction of new drugs’ molecular structures and the key first step in the development of new drugs. This stage aims to obtain each hit series and try to produce more potent and selective compounds which possess pharmacokinetics properties adequate to examine their efficacy in any in vivo models that are available.

Based on our strong background in scientific research, Hit to Lead falls right under our area of expertise. BOC Sciences is committed to helping customers discover high quality lead compounds and shorten the cycle of drug development. There are two basic approaches for the discovery of lead compounds including computer-aided design and screening.