Description & Specifications
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PNAs, or peptide nucleic acids, is an analogue of oligonucleotide in which sugar-phosphate backbone has been replaced by a polyamide chain. Due to the unique backbone of PNA, it can be used in same applications as conventional DNA/RNA. Comparing with DNA, PNAs are neutral in charge, chemically more stable and resistant to DNases and proteases, as well as remaining high sequence specificity, binding activity and lower salt sensitivity. PNAs have been widely used in molecular diagnostics and therapeutics, such as fluorescent in situ hybridization (Fish), single nucleotide polymorphisms (SNPs) detection and antisense therapy. Creative Peptides synthesizes PNA by automated solid-phase methods, as with DNA and RNA oligonucleotide synthesis. The mechanism of PNA synthesis has much in common with solid-phase peptide synthesis. Creative Peptides has rich experience in research and manufacture of PNA and their analogue, including customized PNA synthesis and PNA analog synthesis service. With more than a decade of peptide service allows us to offer the highest level of quality control over the synthesis of every custom ordered product. In the meantime, the expertise of our scientists also makes fast turn around and the best customer support available. |